Who plays tonight? Week 6 college football Friday games TV channel, betting odds

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<p>Who plays tonight? Week 6 college football Friday games TV channel, betting odds</p>

<p>Matthew Glenesk, USA TODAY October 3, 2025 at 5:26 PM</p>

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<p>There are five games Friday night in Week 6 of the college football season, with No. 23 BYU hosting West Virginia in Big 12 action the headliner.</p>

<p>But don't overlook a key matchup in Conference USA as Western Kentucky (4-1, 2-0) takes on Delaware (3-1, 1-0) in a key early-season league clash.</p>

<p>Here's the rest of Friday night's schedule with TV info and betting odds for each game.</p>

<p>College football Week 6 picks: Predictions for Top 25 games include Miami-FSU</p>

<p>College Football Week 6: The six games you can't miss include SEC, ACC rivalries</p>

<p>College football Week 6 Friday night schedule</p>

<p>Odds courtesy of BetMGM.</p>

<p>Charlotte vs South Florida football betting odds, TV channel -</p>

<p>Time: 7 p.m.</p>

<p>TV: ESPN2</p>

<p>Betting odds: South Florida (-28), O/U 55.5</p>

<p>Stream Week 6 of college football with Fubo (free trial)</p>

<p>Western Kentucky vs Delaware football betting odds, TV channel -</p>

<p>Time: 7 p.m.</p>

<p>TV: CBS Sports Network</p>

<p>Betting odds: Delaware (-2.5), O/U 61.5</p>

<p>New Mexico vs San Jose State football betting odds, TV channel -</p>

<p>Time: 10 p.m.</p>

<p>TV: FS1</p>

<p>Betting odds: San Jose State (-2.5), O/U 58.5</p>

<p>West Virginia vs BYU football betting odds, TV channel -</p>

<p>Time: 10:30 p.m.</p>

<p>TV: ESPN</p>

<p>Betting odds: BYU (-20.5); O/U 46.5</p>

<p>Prediction: BYU 41, West Virginia 13</p>

<p>The Mountaineers have looked stunningly bad in their first season of Rich Rodriguez's second go-around at the school, with their two Big 12 losses coming by a combined 65 points. Things won't get any easier against a tough, physical Cougars team that will be playing at altitude. — Craig Meyer, USA TODAY</p>

<p>Colorado State vs San Diego State football betting odds, TV channel -</p>

<p>Time: 10:30 p.m.</p>

<p>TV: CBS Sports Network</p>

<p>Betting odds: San Diego State (-5.5); O/U 41.5</p>

<p>This article originally appeared on USA TODAY: Sports tonight: CFB Week 6 times, TV channel, betting odds, schedule</p>

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